Essential Core Services

• Research and Development
  • Facilitate a pipeline from vectors designed in silico to the physical product.
  • Generate new expression vectors as needed.
  • Develop improved methods for vector production.
  • Compare and contrast new technologies to established technologies.
• Production
  • Assemble custom plasmids for generation of vectors that deliver transgenes, guide RNAs, shRNAs, or gene editing machinery.
  • Prepare recombinant vectors from an extensive and growing catalog. 
  • Purify, titer, and perform quality control assays prior to vector dissemination.
• Education
  • Present technology advances in joint lab meetings, journal clubs, seminars, and webinars.
  • Provide advice concerning the implementation of delivery vectors in study design.
  • Provide protocols and hands-on training for quantifying delivery and editing efficacy.
• Materials archive
  • Maintain an itemized catalogue of vector stocks available for use.
  • Maintain a plasmid database of viral and nonviral expression vectors.