Tracheal

Research Spotlight

Amy Ryan, Associate Professor in Anatomy and Cell Biology and Internal Medicine, Director of the P30 funded Precision Medicine Center for CF and Vice Chair for Research In Anatomy and Cell Biology

Latest Publications

Scientific and Regulatory Policy Committee Points to Consider*: Sample Selection, Assay Design, Data Generation and Interpretation, and Reporting Practices for Chromogenic Immunohistochemical (IHC) Assays in Nonclinical Drug Development

Wednesday, December 31, 2025
Famke Aeffner
Chromogenic immunohistochemistry (IHC) is an important molecular localization assay in biomedical research and nonclinical drug development, enabling the visualization of specific epitopes within tissues. The methodology is widely used in drug target selection, risk assessment, understanding disease biology, and characterizing histopathological findings in nonclinical studies. The Scientific and Regulatory Policy Committee of the Society of Toxicologic Pathology formed a working group to compile...

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