Tracheal

Research Spotlight

Dr. John F. Engelhardt research focuses on the molecular basis of CF and the development of gene therapies for the disease. Notably, Dr. Engelhardt's laboratory was the first to clone ferrets, creating new animal models that have enhanced the study of CF pathologies and potential treatments.

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Research Papers

Durable transgene expression and efficient re-administration after rAAV2.5T-mediated fCFTRDR gene delivery to adult ferret lungs by Yinghua Tang - Anatomy and Cell Biolgy

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Pilot Programs

Pilot programs  provides seed money for research that has not yet reached the stage of maturity necessary for funding by traditional NIH mechanisms such as RO1s and PO1s. Such research ideas should be considered innovative and may potentially be high risk.

Latest Publications

A Versatile Reporter Platform for Evaluating HDR- and NHEJ-Based Genome Editing in Airway Epithelial Cell Cultures Using an rAAV Vector

Friday, June 27, 2025
Soo Yeun Park
Therapeutic gene editing strategies utilize endogenous DNA repair pathways-nonhomologous end joining (NHEJ) or homology-directed repair (HDR)-to introduce targeted genomic modifications. Because HDR is restricted to dividing cells, whereas NHEJ functions in both dividing and non-dividing cells, NHEJ-based approaches are better suited for in vivo gene editing in the largely post-mitotic airway epithelium. Homology-independent targeted insertion (HITI), an NHEJ-based method, offers a promising...

Events

Biology Seminar/Raymond Fong Memorial Lecture: "The body politic: coral reefs and human pregnancy" promotional image

Biology Seminar/Raymond Fong Memorial Lecture: "The body politic: coral reefs and human pregnancy"

Friday, January 23, 2026 3:30pm
Biology Building East
The Department of Biology’s first seminar of the semester is the Raymond Fong Memorial Lecture on Friday, January 23, featuring Dakota (Cody) McCoy, as the speaker. Dr. McCoy is an Assistant Professor in the Department of Ecology & Evolution at the University of Chicago and the Marine Biological Laboratory. Her seminar will be held at 3:30pm in Kollros Auditorium (Room 101), Biology Building East (BBE). A reception with refreshments will be held in the BBE Lobby following the seminar.
ACB Seminar Series - Sadia Islam Mou & Emily Liu promotional image

ACB Seminar Series - Sadia Islam Mou & Emily Liu

Wednesday, January 28, 2026 9:30am to 10:30am
Bowen Science Building

Sadia Islam Mou, a Cell and Developmental Biology Student in the Tootle Lab, will present a seminar titled “Determining the Role of Prostaglandin Signaling During Collective Cell Migration."

Emily Liu, a Cell and Developmental Biology Student in the Ryan Lab, will present a seminar titled “Intra and Intercellular Interactions Driving Lung Remodeling in Pulmonary Lymphangioleiomyomatosis."

ACB Seminar Series - Joy James & Dr. Emma Thornell promotional image

ACB Seminar Series - Joy James & Dr. Emma Thornell

Wednesday, February 4, 2026 9:30am to 10:30am
Bowen Science Building

Joy James, a Cell and Developmental Biology Student in the Stephens Lab, will present a seminar titled “Pro-inflammatory Cytokines Mediate Early Β-cell Dysfunction In Type 1 Diabetes."

Dr. Emma Thornell, a Research Assistant Professor in the Department of Internal Medicine, will present a seminar titled “Sustainable Science: Integrating Sustainability and Innovation in Biomedical Research."

ACB Seminar Series - Dr. Pierre Coulombe promotional image

ACB Seminar Series - Dr. Pierre Coulombe

Wednesday, February 11, 2026 9:30am to 10:30am
Bowen Science Building

Dr. Pierre Coulombe, Professor and Chair of the Department of Cell and Developmental Biology from the University of Michigan, will present a seminar titled "Sequential Expression of Keratins Regulate Progenitor and Differentiating Keratinocytes in Healthy and Diseased Skin."

College of Pharmacy PSET Seminar Series: Bindu Gottam, MS, MBA, RAC

Tuesday, March 24, 2026 11:30am
College of Pharmacy Building

The Department of Pharmaceutical Sciences and Experimental Therapeutics (PSET) in the College of Pharmacy will host a seminar presented by: 

Bindu Gottam, MS, MBA, RAC
Director of Preformulation and Formulation Development
University of Iowa Pharmaceuticals

All are welcome to attend. No pre-registration required.