Tracheal

Research Spotlight

Amy Ryan, Associate Professor in Anatomy and Cell Biology and Internal Medicine, Director of the P30 funded Precision Medicine Center for CF and Vice Chair for Research In Anatomy and Cell Biology

Latest Publications

LUNAR LNP delivery of CFTR mRNA restores channel function and improves mucociliary clearance in ferret cystic fibrosis airways

Thursday, December 25, 2025
Xiaoming Liu
Lipid nanoparticle (LNP)-based delivery of CFTR mRNA holds promise for treating pulmonary manifestations of cystic fibrosis (CF). LUNAR-CFTR is a novel proprietary lipid nanoparticle (LNP) encapsulating codon-optimized human CFTR mRNA for CFTR replacement therapy. In this study, we examined the potential of LUNAR-CFTR for delivering mRNA and restoring CFTR function in primary human and ferret airway epithelia and mucus-laden CF ferret airways. LUNAR effectively delivered CFTR, Cre, and tdTomato...

Events

Anatomy of an Idea - Tom Rutkowski promotional image

Anatomy of an Idea - Tom Rutkowski

Friday, October 9, 2026 12:00pm to 1:00pm
Bowen Science Building
ACB Seminar Series - Joy James promotional image

ACB Seminar Series - Joy James

Wednesday, October 14, 2026 9:30am to 10:30am
Bowen Science Building

Joy James, a Cell and Developmental Biology Graduate Student in Sam Stephen's Lab will present a seminar titled "Proinflammatory Cytokines Induce Golgi Remodeling In Pancreatic Β-cells Beyond Inos-no Signaling."

Anatomy of an Idea - Kathy Andersen promotional image

Anatomy of an Idea - Kathy Andersen

Friday, October 23, 2026 12:00pm to 1:00pm
Bowen Science Building
ACB Seminar Series - Dr. Andrea Page-McCaw promotional image

ACB Seminar Series - Dr. Andrea Page-McCaw

Wednesday, October 28, 2026 9:30am to 10:30am
Bowen Science Building

Dr. Andrea Page-McCaw, Professor and Chair of the Department of Cell & Developmental Biology at Vanderbilt University, will present a seminar titled "From Cell Damage to Cell Fusion: An Unexpected Pathway in Tissue Repair."

Anatomy of an Idea - Kate Kragness promotional image

Anatomy of an Idea - Kate Kragness

Friday, November 13, 2026 12:00pm to 1:00pm
Bowen Science Building